DataSet Record GDS1316: Expression Profiles Data Analysis Tools Sample Subsets
Title: GATA-1 variant role in Down syndrome megakaryocytic leukemias
Cluster AnalysisGDS1316 Cluster Image
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Summary: Analysis of megakaryocytes and their progenitors from mutant E12.5 embryo liver expressing truncated transcription factor GATA-1. Results provide insight into the role of variant GATA-1 (GATA1s) in megakaryocyte hyperproliferation and Down syndrome (DS)-associated leukemias (TMD, DS-AMKL/DS-AML M7).
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Li Z, Godinho FJ, Klusmann JH, Garriga-Canut M et al. Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1. Nat Genet 2005 Jun;37(6):613-9. PMID: 15895080
Reference Series: GSE2433 Sample count: 10
Value type: count Series published: 2005/05/14