DataSet Record GDS1339: Expression Profiles Data Analysis Tools Sample Subsets
Title: T cell anergy induction regulation by Egr-2 and Egr-3 (MG-U74C)
Cluster AnalysisGDS1339 Cluster Image
Summary: Analysis of pooled mRNA (2, 4, 6 hours) from A.E7 T cell clones activated in conditions that promote (anti-TCR) or inhibit (anti-TCR + CsA or PKCi or Combo) anergy induction. Results identify the early growth response gene 2 (Egr-2) and Egr-3 as key positive regulators of T cell anergy induction.
Organism: Mus musculus
Platform: GPL83: [MG_U74Cv2] Affymetrix Murine Genome U74 Version 2 Array
  • Safford M, Collins S, Lutz MA, Allen A et al. Egr-2 and Egr-3 are negative regulators of T cell activation. Nat Immunol 2005 May;6(5):472-80. PMID: 15834410
Reference Series: GSE2323 Sample count: 5
Value type: count Series published: 2005/02/23