Obesity and type 2 diabetes: role of adipogenic gene expression (Mu11K-A)
Summary:
Analysis of lean (C57BL/6J (B6), BTBR, F1 (B6xBTBR)), obese (B6-ob/ob), and obese-diabetic (F2 (B6xBTBR)-ob/ob [increasingly hyperglycemic], BTBR-ob/ob [severely diabetic]) strains. Results identify decreased adipogenic gene expression in obesity and further changes in the progression to diabetes.
Nadler ST, Stoehr JP, Schueler KL, Tanimoto G et al. The expression of adipogenic genes is decreased in obesity and diabetes mellitus. Proc Natl Acad Sci U S A 2000 Oct 10;97(21):11371-6. PMID: 11027337
