DataSet Record GDS1474: Expression Profiles Data Analysis Tools Sample Subsets
Title: Transcription factor Tcf1 knockout effect on pancreatic islets (MG-U74B)
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Summary: Analysis of pancreatic islets from 6 to 8 week old Tcf1 knockouts. Mutations in Tcf1 lead to a subtype of type 2 diabetes called maturity-onset diabetes of the young (MODY) in humans. Results identify potential targets of Tcf1 that may be responsible for mediating pancreatic beta cell growth.
Organism: Mus musculus
Platform: GPL82: [MG_U74Bv2] Affymetrix Murine Genome U74B Version 2 Array
Citation:
  • Akpinar P, Kuwajima S, Krützfeldt J, Stoffel M. Tmem27: a cleaved and shed plasma membrane protein that stimulates pancreatic beta cell proliferation. Cell Metab 2005 Dec;2(6):385-97. PMID: 16330324
Reference Series: GSE3544 Sample count: 4
Value type: count Series published: 2005/12/08