Expression profiling of gallbladders from 12 leptin-deficient obese females following daily treatment with 5 ug/g recombinant leptin for 4 weeks. Studies indicate that leptin plays a role in gallbladder motility. Results provide insight into the role of leptin in gallstone disease.
Swartz-Basile DA, Lu D, Basile DP, Graewin SJ et al. Leptin regulates gallbladder genes related to absorption and secretion. Am J Physiol Gastrointest Liver Physiol 2007 Jul;293(1):G84-90. PMID: 17463181
