Analysis of spt10 null deletion and spt10(C388S) mutants. SPT10 encodes a putative histone acetyltranferase implicated as a global transcription regulator and is involved in chromatin maintenance. The C388S mutation disrupts a predicted zinc finger that may be part of the DNA-binding domain.
Mendiratta G, Eriksson PR, Shen CH, Clark DJ. The DNA-binding domain of the yeast Spt10p activator includes a zinc finger that is homologous to foamy virus integrase. J Biol Chem 2006 Mar 17;281(11):7040-8. PMID: 16415340
