DataSet Record GDS1627: Expression Profiles Data Analysis Tools Sample Subsets
Title: Breast cancer cell lines response to chemotherapeutic drugs: time course
Cluster AnalysisGDS1627 Cluster Image
Summary: Analysis of 4 breast cell lines treated for up to 36 hrs with the chemotherapeutic agents 5-fluorouracil (5FU), doxorubicin (DOX), or etoposide (ETOP), a drug mechanistically similar to DOX. Expression profiles for DOX- and 5FU-treated cells were used to successfully predict the response to ETOP.
Organism: Homo sapiens
Platform: GPL550: UNC compugen oligo array for toxgenomics study
  • Troester MA, Hoadley KA, Parker JS, Perou CM. Prediction of toxicant-specific gene expression signatures after chemotherapeutic treatment of breast cell lines. Environ Health Perspect 2004 Nov;112(16):1607-13. PMID: 15598611
Reference Series: GSE1647 Sample count: 83
Value type: log2 ratio Series published: 2004/09/28