MicroRNA miR-122 antisense inhibition effect on livers
Summary:
Analysis of liver from C57BL/6 adult males treated with an antisense oligonucleotide (ASO) targeting liver-specific microRNA (miRNA) miR-122. miR-122 is expressed at high levels in the adult liver, making up 70% of all miRNA. Results provide insight into the role of miR-122 in the adult liver.
GPL2897:
GE Healthcare/Amersham Biosciences CodeLink™ Mouse Whole Genome Bioarray
Citation:
Esau C, Davis S, Murray SF, Yu XX et al. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab 2006 Feb;3(2):87-98. PMID: 16459310
