Platelet-derived growth factor effect on fibroblasts: time course
Summary:
Expression profiling of AG01518 foreskin fibroblasts at various time points up to 24 hours following stimulation with 10 ng/ml platelet-derived growth factor (PDGF). PDGF is a potent mitogen for fibroblasts and other cells of mesenchymal origin. Results identify genes regulated by PDGF.
Demoulin JB, Ericsson J, Kallin A, Rorsman C et al. Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins. J Biol Chem 2004 Aug 20;279(34):35392-402. PMID: 15213220
