Ovarian germ line stem cells expanded by Dpp overexpression and bam mutation
Summary:
Analysis of purified ovarian germ line stem cells (GSCs) expanded by overexpression of the bone morphogenetic protein Dpp or by mutating the bam gene. Kc tissue culture cells also examined. Dpp represses bam transcription. Results provide insight into the mechanisms of GSC maintenance and function.
Kai T, Williams D, Spradling AC. The expression profile of purified Drosophila germline stem cells. Dev Biol 2005 Jul 15;283(2):486-502. PMID: 15927177
