Keratinocyte response to GLI1 and GLI2 induction: time course
Summary:
Analysis of keratinocyte HaCaT cells at 24 and 72 hours following induction of GLI1 or a constitutively active form of GLI2 from a tetracycline inducible promoter. GLI transcription factors mediate the hedgehog signal in development and carcinogenesis.
Eichberger T, Sander V, Schnidar H, Regl G et al. Overlapping and distinct transcriptional regulator properties of the GLI1 and GLI2 oncogenes. Genomics 2006 May;87(5):616-32. PMID: 16434164
