Airway disease trait manifestation in various genetic backgrounds: lungs (MG-U74B)
Summary:
Analysis of lungs of animals exhibiting extremes in airway hyperreactivity, goblet cell metaplasia, or both. Animals were derived from an intercross of an F1 hybrid strain, generated by crossing C57Bl/6J and Balb/cJ strains. Results provide insight into the pathogenesis of complex airway diseases.
GPL82:
[MG_U74Bv2] Affymetrix Murine Genome U74B Version 2 Array
Citation:
Patel AC, Morton JD, Kim EY, Alevy Y et al. Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members. Physiol Genomics 2006 May 16;25(3):502-13. PMID: 16569774