Hypoxia-inducible factors-1 and -2 overexpression effect on embryonic kidney cells
Summary:
Analysis of HEK293T embryonic kidney cells subjected to hypoxia or overexpressing hypoxia-inducible factor (HIF)-1, degradation resistant HIF-1, or HIF-2. Results provide insight into the respective roles of HIF-1 and HIF-2 in the cellular response to hypoxia.
Wang V, Davis DA, Haque M, Huang LE et al. Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells. Cancer Res 2005 Apr 15;65(8):3299-306. PMID: 15833863
