Analysis of hippocampi of 2-month-old young and 15-month-old middle-aged animals. The hippocampal formation is one of the brain areas most affected by aging. Results provide insight into molecular changes accompanying the early stages of age-related memory decline.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Verbitsky M, Yonan AL, Malleret G, Kandel ER et al. Altered hippocampal transcript profile accompanies an age-related spatial memory deficit in mice. Learn Mem 2004 May-Jun;11(3):253-60. PMID: 15169854