DataSet Record GDS2094: Expression Profiles Data Analysis Tools Sample Subsets
Title: Pregnane X receptor agonist effect on the liver (RAE230B)
Cluster AnalysisGDS2094 Cluster Image
Summary: Analysis of livers of animals treated with pregnenolone 16alpha-carbonitrile (PCN), a pregnane X receptor (NR1I2) agonist. NR1I2 is a member of the nuclear receptor family of ligand-activated transcription factors, and regulates the transcription of genes encoding xenobiotic metabolizing enzymes.
Organism: Rattus norvegicus
Platform: GPL342: [RAE230B] Affymetrix Rat Expression 230B Array
  • Guzelian J, Barwick JL, Hunter L, Phang TL et al. Identification of genes controlled by the pregnane X receptor by microarray analysis of mRNAs from pregnenolone 16alpha-carbonitrile-treated rats. Toxicol Sci 2006 Dec;94(2):379-87. PMID: 16997903
Reference Series: GSE4959 Sample count: 9
Value type: count Series published: 2006/06/03