Lung response to cigarette smoke: dose response (RAE230B)
Summary:
Analysis of lungs of animals exposed to 300 or 600 ug total particulate matter (TPM)/l of cigarette smoke (CS) for 13 weeks and allowed to recover 2, 6, or 20 hours after the last exposure. Results provide insight into mechanisms involved in the onset and development of CS-related diseases.
GPL342:
[RAE230B] Affymetrix Rat Expression 230B Array
Citation:
Gebel S, Gerstmayer B, Kuhl P, Borlak J et al. The kinetics of transcriptomic changes induced by cigarette smoke in rat lungs reveals a specific program of defense, inflammation, and circadian clock gene expression. Toxicol Sci 2006 Oct;93(2):422-31. PMID: 16870687
