Intestinal absorptive cell model response to iron deficiency and overload
Summary:
Analysis of intestinal CaCo-2 cell line grown in medium free of iron or supplemented with hemin to mimic iron overload. Intestinal iron absorption is crucial for systemic iron homeostasis. Results provide insight into molecular mechanisms regulating iron metabolism.
GPL887:
Agilent-012097 Human 1A Microarray (V2) G4110B (Feature Number version)
Citation:
Chicault C, Toutain B, Monnier A, Aubry M et al. Iron-related transcriptomic variations in CaCo-2 cells, an in vitro model of intestinal absorptive cells. Physiol Genomics 2006 Jun 16;26(1):55-67. PMID: 16638840
