Analysis of heart left ventricles (LVs) of animals with pressure overload LV hypertrophy (LVH) caused by transverse aortic constriction. Pressure overload on the heart resulting from chronic hypertension or aortic stenosis is a stimulus for LVH. Results provide insight into the pathogenesis of LVH.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Mirotsou M, Dzau VJ, Pratt RE, Weinberg EO. Physiological genomics of cardiac disease: quantitative relationships between gene expression and left ventricular hypertrophy. Physiol Genomics 2006 Oct 3;27(1):86-94. PMID: 16835353