Caffeine and rapamycin effect on various wild type strains
Summary:
Analysis of W303, S288c, and Sigma 2000 wild type strains treated with rapamycin or caffeine. Results provide insight into the influence of genetic background on the response to each drug.
Reinke A, Chen JC, Aronova S, Powers T. Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p. J Biol Chem 2006 Oct 20;281(42):31616-26. PMID: 16923813
