Targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide effect on various organs
Summary:
Analysis of normal livers, lungs, and mammary glands from Sprague Dawleys treated with targretin (TGR), 9-cis retinoic acid (9cRA), or 4-hydroxyphenylretinamide (4HPR). Results provide insight into the molecular basis of the varying chemopreventive anti-cancer effects of these agents.
Wang Y, Yao R, Maciag A, Grubbs CJ et al. Organ-specific expression profiles of rat mammary gland, liver, and lung tissues treated with targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide. Mol Cancer Ther 2006 Apr;5(4):1060-72. PMID: 16648578
