DataSet Record GDS2391: Expression Profiles Data Analysis Tools Sample Subsets
Title: PGC-1alpha transcriptional coactivator null mutation effect on the brain striatum
Cluster AnalysisGDS2391 Cluster Image
Summary: Analysis of brain striatum of PGC-1alpha transcriptional coactivator null mutants. PGC-1alpha regulates several metabolic processes. Altered energy metabolism is implicated in Huntington's disease (HD). Results provide insight into the role of PGC-1alpha in HD pathogenesis.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
  • Cui L, Jeong H, Borovecki F, Parkhurst CN et al. Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell 2006 Oct 6;127(1):59-69. PMID: 17018277
Reference Series: GSE5786 Sample count: 6
Value type: count Series published: 2006/10/05