Glucosamine and interleukin-1 beta effect on chondrocytes
Summary:
Analysis of cultured articular chondrocytes treated with glucosamine for 6 hours and then by interleukin-1 beta for 14 hours. Cytokines, such as interleukin-1 (IL-1), contribute to the pathogenesis of osteoarthritis. Results provide insight into the anti-arthritic properties of glucosamine.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Gouze JN, Gouze E, Popp MP, Bush ML et al. Exogenous glucosamine globally protects chondrocytes from the arthritogenic effects of IL-1beta. Arthritis Res Ther 2006;8(6):R173. PMID: 17109745