B-cell chronic lymphocytic leukemia cell type and prognosis
Summary:
Analysis of B-cell chronic lymphocytic leukemia (B-CLL) cells that express or do not express zeta-associated protein (ZAP-70) and CD38. The prognosis of patients with ZAP-70-CD38- B-CLL cells is good, those with ZAP-70+CD38+ B-CLL cells is poor.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Hüttmann A, Klein-Hitpass L, Thomale J, Deenen R et al. Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression status. Leukemia 2006 Oct;20(10):1774-82. PMID: 16932341