Analysis of brain frontal cortices of individuals with Rett syndrome (RTT). RTT is an X-linked neurodevelopmental disorder linked to heterozygous de novo mutations in MECP2, a gene encoding methyl-CpG-binding protein 2. Results provide insight into molecular pathogenesis of RTT.
GPL8300:
[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Citation:
Deng V, Matagne V, Banine F, Frerking M et al. FXYD1 is an MeCP2 target gene overexpressed in the brains of Rett syndrome patients and Mecp2-null mice. Hum Mol Genet 2007 Mar 15;16(6):640-50. PMID: 17309881
