DataSet Record GDS2648: Expression Profiles Data Analysis Tools Sample Subsets
Title: Palmitate effect on myoblast cell line
Cluster AnalysisGDS2648 Cluster Image
Summary: Analysis of myoblasts treated with the saturated fatty acid palmitate. Muscle expression of PPAR coactivator 1 (PGC-1) is reduced in models of obesity. Palmitate decreases the expression of PGC-1. Results provide insight into the molecular basis of the link between overnutrition, obesity, and PGC-1.
Organism: Mus musculus
Platform: GPL8321: [Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array
  • Crunkhorn S, Dearie F, Mantzoros C, Gami H et al. Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation. J Biol Chem 2007 May 25;282(21):15439-50. PMID: 17416903
Reference Series: GSE6766 Sample count: 6
Value type: count Series published: 2007/01/18