Signal transduction adaptor MyD88 deficient lung response to Chlamydia pneumoniae infection
Summary:
Analysis of lungs from MyD88 null mutants following Chlamydia pneumoniae infection. Toll-like receptors and key adaptor protein MyD88 play a critical role in inducing immunity against this microorganism. Results provide insight into the molecular mechanisms underlying this MyD88-mediated induction.
Rodríguez N, Mages J, Dietrich H, Wantia N et al. MyD88-dependent changes in the pulmonary transcriptome after infection with Chlamydia pneumoniae. Physiol Genomics 2007 Jul 18;30(2):134-45. PMID: 17374847
