Analysis of p53 mutant embryos exposed to gamma radiation. Within 90 minutes of radiation exposure, apoptosis is observed in embryonic and post-embryonic tissues of wild type but not p53 mutants. Results provide insight into the molecular basis of this p53-dependent apoptogenic response.
Akdemir F, Christich A, Sogame N, Chapo J et al. p53 directs focused genomic responses in Drosophila. Oncogene 2007 Aug 9;26(36):5184-93. PMID: 17310982
