Formaldehyde effect on nasal epithelium: dose response and time course
Summary:
Analysis of nasal epithelia exposed to various doses of the carcinogenic pollutant formaldehyde for up to 19 days. Results used as a case study to validate a method that integrates benchmark dose calculations with gene ontology analysis to examine genomic dose-response data.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Thomas RS, Allen BC, Nong A, Yang L et al. A method to integrate benchmark dose estimates with genomic data to assess the functional effects of chemical exposure. Toxicol Sci 2007 Jul;98(1):240-8. PMID: 17449896
