Analysis of mast cells isolated from the pancreatic lymph nodes of 60 day old prediabetic BioBiobreeding (BB) DR lyp/lyp animals. The BB DR lyp/lyp strain is a model for type 1 diabetes mellitus (T1DM). Results provide insight into the role of mast cells in the pathogenesis of T1DM.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Geoffrey R, Jia S, Kwitek AE, Woodliff J et al. Evidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the BioBreeding rat. J Immunol 2006 Nov 15;177(10):7275-86. PMID: 17082646