Dexamethasone effect on fetal chondrocytes in vitro: time course
Summary:
Analysis of primary cultured fetal chondrocytes treated with pharmacological doses of dexamethasone (DEX) for 6 and 24 hours. DEX is a synthetic glucorticoid (GC) receptor agonist. Results provide insight into the effects of pharmacological GC on chondrocytes.
James CG, Ulici V, Tuckermann J, Underhill TM et al. Expression profiling of Dexamethasone-treated primary chondrocytes identifies targets of glucocorticoid signalling in endochondral bone development. BMC Genomics 2007 Jul 1;8:205. PMID: 17603917