DataSet Record GDS2827: Expression Profiles Data Analysis Tools Sample Subsets
Title: ERalpha-negative ERbeta-positive breast carcinoma response to tamoxifen
Cluster AnalysisGDS2827 Cluster Image
Summary: Analysis of estrogen receptor (ER) alpha negative ERbeta-positive breast cancer tumors from patients treated with tamoxifen for 2 years. Unlike ERalpha-negative ERbeta-negative breast cancers, ERalpha-negative ERbeta-positive cancers respond favorably to tamoxifen treatment.
Organism: Homo sapiens
Platform: GPL3883: Swegene Human 27K RAP UniGene188 array
  • Gruvberger-Saal SK, Bendahl PO, Saal LH, Laakso M et al. Estrogen receptor beta expression is associated with tamoxifen response in ERalpha-negative breast carcinoma. Clin Cancer Res 2007 Apr 1;13(7):1987-94. PMID: 17404078
  • Honeth G, Bendahl PO, Ringnér M, Saal LH et al. The CD44+/CD24- phenotype is enriched in basal-like breast tumors. Breast Cancer Res 2008;10(3):R53. PMID: 18559090
Reference Series: GSE6577 Sample count: 88
Value type: log2 ratio Series published: 2007/04/01