Wip1 mutant embryonic fibroblast response to gamma radiation
Summary:
Analysis of Wip1 mutant embryonic fibroblasts following 4 hour after 5 Gy of gamma irradiation. Wip1 is a p53-induced phosphatase overexpressed in several human tumor types.
Lu X, Ma O, Nguyen TA, Jones SN et al. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop. Cancer Cell 2007 Oct;12(4):342-54. PMID: 17936559
