DataSet Record GDS2874: Expression Profiles Data Analysis Tools Sample Subsets
Title: D-3-phosphoglycerate dehydrogenase deficiency effect on the embryonic head
Cluster AnalysisGDS2874 Cluster Image
Summary: Analysis of embryonic head tissue lacking D-3-phosphoglycerate dehydrogenase (Phgdh). Mutations in human PHGDH gene cause serine deficiency disorders like congenital microcephaly and psychomotor retardation. Results provide insight into the pathogenesis of SDD.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
  • Furuya S, Yoshida K, Kawakami Y, Yang JH et al. Inactivation of the 3-phosphoglycerate dehydrogenase gene in mice: changes in gene expression and associated regulatory networks resulting from serine deficiency. Funct Integr Genomics 2008 Aug;8(3):235-49. PMID: 18228065
Reference Series: GSE8555 Sample count: 8
Value type: count Series published: 2007/07/25