Analysis of a highly immune-resistant cancer cell line. The resistant cell line is produced by subjecting a susceptible cell line to multiple rounds of in vivo immune selection. Results provide insight into the molecular mechanisms underlying tumor immune evasion.
Lin KY, Lu D, Hung CF, Peng S et al. Ectopic expression of vascular cell adhesion molecule-1 as a new mechanism for tumor immune evasion. Cancer Res 2007 Feb 15;67(4):1832-41. PMID: 17308126