Testis response to histone deacetylase inhibitor trichostatin A: time course
Summary:
Analysis of testes at various time points up to 10 hours following subcutaneous injection of the histone deacetylase inhibitor trichostatin A (TSA). TSA treatment is followed by infertility due to the apoptosis of pachytene spermatocytes.
GPL4053:
GE Healthcare/Amersham Biosciences CodeLink UniSet Mouse I Bioarray 10K (2004)
Citation:
Fenic I, Hossain HM, Sonnack V, Tchatalbachev S et al. In vivo application of histone deacetylase inhibitor trichostatin-a impairs murine male meiosis. J Androl 2008 Mar-Apr;29(2):172-85. PMID: 18046049
