DataSet Record GDS2963: Expression Profiles Data Analysis Tools Sample Subsets
Title: Vincristine-sensitive and resistant ovarian carcinoma cell lines
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Summary: Analysis of the vincristine-sensitive SKOV3 ovarian carcinoma cell line and its vincristine-resistant derivative. Vincristine is a chemotherapeutic agent used for the treatment of cancer. Results provide insight into the molecular mechanisms underlying the emergence of multidrug resistance.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citations:
  • Buys TP, Chari R, Lee EH, Zhang M et al. Genetic changes in the evolution of multidrug resistance for cultured human ovarian cancer cells. Genes Chromosomes Cancer 2007 Dec;46(12):1069-79. PMID: 17726699
  • Ingemarsdotter CK, Tookman LA, Browne A, Pirlo K et al. Paclitaxel resistance increases oncolytic adenovirus efficacy via upregulated CAR expression and dysfunctional cell cycle control. Mol Oncol 2015 Apr;9(4):791-805. PMID: 25560085
Reference Series: GSE7556 Sample count: 4
Value type: count Series published: 2007/08/24