DataSet Record GDS2970: Expression Profiles Data Analysis Tools Sample Subsets
Title: Polyamide-chlorambucil conjugate 1R-Chl effect on leukemia cell line
Cluster AnalysisGDS2970 Cluster Image
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Summary: Analysis of leukemia K562 cells treated with the polyamide-chlorambucil conjugate 1R-Chl. 1R-Chl down-regulates transcription of the human histone H4c gene and inhibits the growth of several cancer cell lines in vitro.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
  • Chou CJ, Farkas ME, Tsai SM, Alvarez D et al. Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia. Mol Cancer Ther 2008 Apr;7(4):769-78. PMID: 18413791
Reference Series: GSE8832 Sample count: 6
Value type: count Series published: 2007/08/22