Bone morphogenetic protein 4 effect on a stem cell line
Summary:
Analysis of C3H10T1/2 (10T1/2) stem cells committed to the adipocyte lineage by treatment with bone morphogenetic protein 4 (BMP-4), a member of the transforming growth factor-beta superfamily. Results provide insight into the molecular mechanisms underlying adipocyte commitment in a stem cell line.
Otto TC, Bowers RR, Lane MD. BMP-4 treatment of C3H10T1/2 stem cells blocks expression of MMP-3 and MMP-13. Biochem Biophys Res Commun 2007 Feb 23;353(4):1097-104. PMID: 17204246