DataSet Record GDS3126: Expression Profiles Data Analysis Tools Sample Subsets
Title: Radioresistant tumor response to interferons
Cluster AnalysisGDS3126 Cluster Image
Summary: Analysis of nu61 radioresistant tumors following treatment with a mixture of interferons (IFNs) alpha, beta, and gamma. Nu61 tumors derived from the radiosensitive squamous cell carcinoma cell line SCC61. Results provide insight into the role of the IFN signaling pathway in tumor radioresistance.
Organism: Homo sapiens
Platform: GPL96: [HG-U133A] Affymetrix Human Genome U133A Array
  • Khodarev NN, Beckett M, Labay E, Darga T et al. STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells. Proc Natl Acad Sci U S A 2004 Feb 10;101(6):1714-9. PMID: 14755057
  • Khodarev NN, Minn AJ, Efimova EV, Darga TE et al. Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells. Cancer Res 2007 Oct 1;67(19):9214-20. PMID: 17909027
Reference Series: GSE9714 Sample count: 8
Value type: count Series published: 2007/11/28