Analysis of C2C12 myoblast cells treated with reversine. Reversine induces dedifferentiation of C2C12 myoblasts and the subsequent redifferentiation to become multipotent mesenchymal progenitor cells. Results provide insight into the molecular mechanisms underlying reversine's effects.
Lee EK, Bae GU, You JS, Lee JC et al. Reversine increases the plasticity of lineage-committed cells toward neuroectodermal lineage. J Biol Chem 2009 Jan 30;284(5):2891-2901. PMID: 19015271
