Analysis of young, untreated metaphase II (MII) oocytes. Results provide insight into the baseline of genes expressed in in vivo matured oocytes and into the molecular mechanisms underlying biological processes such as oogenesis, folliculogenesis, fertilization, and embryonic development.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citations:
Kocabas AM, Crosby J, Ross PJ, Otu HH et al. The transcriptome of human oocytes. Proc Natl Acad Sci U S A 2006 Sep 19;103(38):14027-32. PMID: 16968779
Gonzalez-Muñoz E, Arboleda-Estudillo Y, Otu HH, Cibelli JB. Cell reprogramming. Histone chaperone ASF1A is required for maintenance of pluripotency and cellular reprogramming. Science 2014 Aug 15;345(6198):822-5. PMID: 25035411
