Angiopoietin-1 stimulation of vascular endothelial cells
Summary:
Analysis of HUVECs upon Ang1 stimulation in the presence (confluent) or absence (sparse) of cell-cell contacts. The Ang1-Tie2 system is implicated in both vascular quiescence and angiogenesis. Results provide insight into Ang1 signalling in the presence or absence of cell-cell contacts.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Fukuhara S, Sako K, Minami T, Noda K et al. Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1. Nat Cell Biol 2008 May;10(5):513-26. PMID: 18425120
