Chromatin remodeling component BAF250a deficiency effect on embryonic stem cells in vitro
Summary:
Analysis of embryonic stem (ES) cells deleted for BAF250a in vitro. BAF250 is a component of the BAF chromatin remodeling complex. Results provide insight into the role of BAF250a in ES cell self-renewal and differentiation.
Gao X, Tate P, Hu P, Tjian R et al. ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a. Proc Natl Acad Sci U S A 2008 May 6;105(18):6656-61. PMID: 18448678