Retinal pigment epithelium (RPE) response to light damage
Summary:
Analysis of RPE from BALBc mice, exposed to 6000 lux cool white light for 1.5 h and allowed to recover for 24 hrs in the dark. RPE is the site of pathologic processes in many retinal disorders. Results provide insight into the molecular response to light damage of the RPE.
Rattner A, Toulabi L, Williams J, Yu H et al. The genomic response of the retinal pigment epithelium to light damage and retinal detachment. J Neurosci 2008 Sep 24;28(39):9880-9. PMID: 18815272