Gastrointestinal tract response to cytotoxic chemotherapy: time course
Summary:
Analysis of the gastrointestinal tracts of animals up to 72 hours following treatment with the chemotherapy agent irinotecan to induce gastrointestinal mucositis (GM). GM is caused by the cytotoxic effects of cancer chemotherapy and radiotherapy. Results provide insight into the pathogenesis of GM.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Bowen JM, Gibson RJ, Tsykin A, Stringer AM et al. Gene expression analysis of multiple gastrointestinal regions reveals activation of common cell regulatory pathways following cytotoxic chemotherapy. Int J Cancer 2007 Oct 15;121(8):1847-56. PMID: 17594691
