DataSet Record GDS3495: Expression Profiles Data Analysis Tools Sample Subsets
Title: Progerin expression in a hTERT-immortalized skin fibroblast cell line: time course
Cluster AnalysisGDS3495 Cluster Image
Summary: Analysis of skin fibroblasts induced to express GFP-progerin for up to 10 days. Progerin is a mutant form of lamin A and the causal agent of premature-ageing disease Hutchinson-Gilford Progeria Syndrome (HGPS). Results provide insight into molecular mechanisms underlying this pathological effect.
Organism: Homo sapiens
Platform: GPL2895: GE Healthcare/Amersham Biosciences CodeLink Human Whole Genome Bioarray
  • Scaffidi P, Misteli T. Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing. Nat Cell Biol 2008 Apr;10(4):452-9. PMID: 18311132
Reference Series: GSE10123 Sample count: 12
Value type: count Series published: 2008/02/09