DataSet Record GDS3534: Expression Profiles Data Analysis Tools Sample Subsets
Title: Lymphatic endothelial cell response to Prox1 and NR2F2 depletion
Cluster AnalysisGDS3534 Cluster Image
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Summary: Analysis of lymphatic endothelial cells (LECs) depleted for Prox1, NR2F2, or both regulators. LECs are derived from venous endothelial cells (VECs). Prox1 and NR2F2 regulate LEC and VEC development, respectively. Results provide insight into the role of NR2F2 and Prox1 in maintaining LEC phenotypes.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citations:
  • Lee S, Kang J, Yoo J, Ganesan SK et al. Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate. Blood 2009 Feb 19;113(8):1856-9. PMID: 18815287
  • Yoo J, Lee HN, Choi I, Choi D et al. Opposing regulation of PROX1 by interleukin-3 receptor and NOTCH directs differential host cell fate reprogramming by Kaposi sarcoma herpes virus. PLoS Pathog 2012;8(6):e1002770. PMID: 22719258
Reference Series: GSE12846 Sample count: 4
Value type: count Series published: 2008/09/20