Polybrominated diphenyl ethers effect on adrenocortical carcinoma cell line
Summary:
Analysis of H295R adrenocortical carcinoma cells treated with the hydroxylated polybrominated biphenyl ether (PBDE) 2-OH-BDE47 or 2-OH-BDE85. PBDEs are used as flame retardants in various products. The two PBDEs are cytotoxic. Results provide insight into the molecular basis of PBDE cytotoxicity.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Song R, Duarte TL, Almeida GM, Farmer PB et al. Cytotoxicity and gene expression profiling of two hydroxylated polybrominated diphenyl ethers in human H295R adrenocortical carcinoma cells. Toxicol Lett 2009 Feb 25;185(1):23-31. PMID: 19095052
