Beta-catenin depletion effect on multiple myeloma cell line
Summary:
Analysis of multiple myeloma MM1.S cells depleted for beta-catenin. Beta-catenin is an effector of the Wnt signaling pathway. Results provide insight into the role of Wnt/beta-catenin signaling in the progression of multiple myeloma.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Dutta-Simmons J, Zhang Y, Gorgun G, Gatt M et al. Aurora kinase A is a target of Wnt/beta-catenin involved in multiple myeloma disease progression. Blood 2009 Sep 24;114(13):2699-708. PMID: 19652203
