DataSet Record GDS3582: Expression Profiles Data Analysis Tools Sample Subsets
Title: PTEN heterozygosity effect on Smoothened-active mouse model
Cluster AnalysisGDS3582 Cluster Image
Summary: Analysis of medulloblastoma (MB) tumors from mice heterozygous for PTEN. SmoA1 +; Pten +/- mice exhibited decreased survival, an increased incidence, and a shorter time to onset of symptoms, compared to SmoA1 +; Pten +/+ mice. Results provide insight into the role of PTEN in the pathogenesis of MB.
Organism: Mus musculus
Platform: GPL6887: Illumina MouseWG-6 v2.0 expression beadchip
  • Castellino RC, Barwick BG, Schniederjan M, Buss MC et al. Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma. PLoS One 2010 May 26;5(5):e10849. PMID: 20520772
Reference Series: GSE19059 Sample count: 12
Value type: count Series published: 2009/11/21